Antidepressant amitriptyline‐induced matrix metalloproteinase‐9 activation is mediated by Src family tyrosine kinase, which leads to glial cell line‐derived neurotrophic factor mRNA expression in rat astroglial cells

• Հիմնական հեղինակներ: Hiromi Abe (Հեղինակ), Naoto Kajitani (Հեղինակ), Mami Okada‐Tsuchioka (Հեղինակ), Wataru Omori (Հեղինակ), Masahide Yatsumoto (Հեղինակ), Minoru Takebayashi (Հեղինակ)
• Ձևաչափ: Գիրք
• Հրապարակվել է: Wiley, 2019-09-01T00:00:00Z.
• Խորագրեր: article
• Առցանց հասանելիություն: Connect to this object online.

Abstract Background Astrocytes have been implicated in the pathophysiology of mood disorders and in the mechanism of the pharmacological effects of antidepressant drugs by the production of neurotrophic/growth factors. Previous studies have identified astrocyte‐expressed Gαi/o‐coupled lysophosphatid...