HybridSPE: A novel technique to reduce phospholipid-based matrix effect in LC-ESI-MS Bioanalysis

• Main Authors: Shafeeque Ahmad (Author), Harsh Kalra (Author), Amit Gupta (Author), Bharat Raut (Author), Arshad Hussain (Author), Md Akhlaquer Rahman (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

When complex biological materials are analyzed without an adequate sample preparation technique, MS signal and response undergo significant alteration and result in poor quantification and assay. This problem generally takes place due to the presence of several endogenous materials component in samp...