Design, synthesis, biological evaluation and molecular docking study of 2,4-diarylimidazoles and 2,4-bis(benzyloxy)-5-arylpyrimidines as novel HSP90 N-terminal inhibitors

The molecular chaperone HSP90 plays an essential role in cancer occurrence and development. Therefore, it is an important target for the development of anticancer drugs. 1,3-Dibenzyl-2-aryl imidazolidine (8) is a previously reported inhibitor of HSP90; however, its anticancer activity is poor. In th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Man Yang (Author), Chenyao Li (Author), Yajing Li (Author), Chen Cheng (Author), Meiyun Shi (Author), Lei Yin (Author), Hongyu Xue (Author), Yajun Liu (Author)
Formato: Livro
Publicado em: Taylor & Francis Group, 2022-12-01T00:00:00Z.
Assuntos:
Acesso em linha:Connect to this object online.
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Internet

Connect to this object online.

3rd Floor Main Library

Detalhes do Exemplar 3rd Floor Main Library
Área/Cota: A1234.567
Cód. Barras: 1 Disponível