Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1

• Main Authors: Ryo Kubota (Author), Michael J. Reid (Author), Kuo Lee Lieu (Author), Mark Orme (Author), Christine Diamond (Author), Niklas Tulberg (Author), Susan H. Henry (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation. Inhibition of VAP-1 oxidative deamination has become an attractive target for anti-inflammatory therapy with demonstrated efficacy...