Evaluation of Benzguinols as Next-Generation Antibiotics for the Treatment of Multidrug-Resistant Bacterial Infections

• Main Authors: Hang Thi Nguyen (Author), Mahmud T. Morshed (Author), Daniel Vuong (Author), Andrew Crombie (Author), Ernest Lacey (Author), Sanjay Garg (Author), Hongfei Pi (Author), Lucy Woolford (Author), Henrietta Venter (Author), Stephen W. Page (Author), Andrew M. Piggott (Author), Darren J. Trott (Author), Abiodun D. Ogunniyi (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our recent focus on the "lost antibiotic" unguinol and related nidulin-family fungal natural products identified two semisynthetic derivatives, benzguinols A and B, with unexpected in vitro activity against <i>Staphylococcus aureus</i> isolates either susceptible or resistant t...