Anti-Inflammatory Effects of Hyperbaric Oxygenation during DSS-Induced Colitis in BALB/c Mice Include Changes in Gene Expression of HIF-1α, Proinflammatory Cytokines, and Antioxidative Enzymes

• Main Authors: Sanja Novak (Author), Ines Drenjancevic (Author), Rosemary Vukovic (Author), Zoltán Kellermayer (Author), Anita Cosic (Author), Maja Tolusic Levak (Author), Péter Balogh (Author), Filip Culo (Author), Martina Mihalj (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) and nitrogen species have an indispensable role in regulating cell signalling pathways, including transcriptional control via hypoxia inducible factor-1α (HIF-1α). Hyperbaric oxygenation treatment (HBO2) increases tissue oxygen content and leads to enhanced ROS producti...