Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Signaling Pathway

• Main Authors: Jingjing Ye (Author), Wei Ai (Author), Fenglin Zhang (Author), Xiaotong Zhu (Author), Gang Shu (Author), Lina Wang (Author), Ping Gao (Author), Qianyun Xi (Author), YongLiang Zhang (Author), Qingyan Jiang (Author), Songbo Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Porcine bone marrow mesenchymal stem cells (pBMSCs) have the potential for application in regenerative medicine. This study aims to investigate the effects of extracellular calcium (Ca2+o) on pBMSCs proliferation and to explore the possible underlying mechanisms. The results demonstrated that 4 mM C...