High-fat diets enhance and delay ursodeoxycholic acid absorption but elevate circulating hydrophobic bile salts

• Main Authors: Liang Huang (Author), Wei Wei (Author), Xiaomei Huang (Author), Xuejing Li (Author), Haisha Liu (Author), Lanlan Gui (Author), Jinping Jiang (Author), Linfei Wan (Author), Xiangxiang Zhou (Author), Jingsong Ding (Author), Xuehua Jiang (Author), Bikui Zhang (Author), Ke Lan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ursodeoxycholic acid (UDCA) is a natural drug essential for the treatment of cholestatic liver diseases. The food effects on the absorption of UDCA and the disposition of circulating bile salts remain unclear despite its widespread global uses. This study aims to investigate the effects...