Metformin reduces androgen receptor and upregulates homeobox A10 expression in uterine endometrium in women with polycystic ovary syndrome

• Main Authors: Miki Ohara (Author), Hiromi Yoshida-Komiya (Author), Miho Ono-Okutsu (Author), Akiko Yamaguchi-Ito (Author), Toshifumi Takahashi (Author), Keiya Fujimori (Author)
• Format: Book
• Published: BMC, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) causes anovulation and is associated with a reduced clinical pregnancy rate. Metformin, which is widely used for treating PCOS, can lead to successful pregnancy by restoring the ovulation cycle and possibly improving endometrial abnormality during...