Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques

• Main Authors: Sultan M. Alshehri (Author), Faiyaz Shakeel (Author), Mohamed A. Ibrahim (Author), Ehab M. Elzayat (Author), Mohammad Altamimi (Author), Kazi Mohsin (Author), Osaid T. Almeanazel (Author), Musaed Alkholief (Author), Abdullah Alshetaili (Author), Bader Alsulays (Author), Fars K. Alanazi (Author), Ibrahim A. Alsarra (Author)
• Format: Book
• Published: Elsevier, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apigenin (APG) is a poorly soluble bioactive compound/nutraceutical which shows poor bioavailability upon oral administration. Hence, the objective of this research work was to develop APG solid dispersions (SDs) using different techniques with the expectation to obtain improvement in its in vitro d...