Periodic fever syndromes: beyond the single gene paradigm

• Main Authors: Clara Westwell-Roper (Author), Iwona Niemietz (Author), Lori B. Tucker (Author), Kelly L. Brown (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease in Canada and is characterized by a clinical syndrome of episodic inflammatory symptoms. Traditionally, the disease is defined by autosomal recessive inheritance of MEFV gene variants, yet FMF also not...