Safety Pharmacology Study of ET-26 Hydrochloride, a Potential Drug for Intravenous General Anesthesia, in Rats and Beagle Dogs

• Главные авторы: YuJun Zhang (Автор), YingYing Jiang (Автор), Pan Chang (Автор), Yi Kang (Автор), DeYing Gong (Автор), Jin Liu (Автор), WenSheng Zhang (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Предметы: article
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Background: ET-26 hydrochloride (ET-26HCl), a class 1 new drug, was developed to reserve the advantages of etomidate with a mild adrenocortical inhibition.Purpose: this study was to evaluate the potential adverse effects on the cardiovascular system of beagle dogs and the respiratory and central ner...