Rapid, label‐free enrichment of lymphocytes in a closed system using a flow‐through microfluidic device

• Автори: Anton Mukhamedshin (Автор), Riley C. Reddington (Автор), Mai T. P. Dinh (Автор), Kumar Abhishek (Автор), Mubasher Iqbal (Автор), Marc Manheim (Автор), Sean C. Gifford (Автор), Sergey S. Shevkoplyas (Автор)
• Формат: Книга
• Опубліковано: Wiley, 2024-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract The majority of adoptive cellular therapies are produced from peripheral mononuclear cells obtained via leukapheresis and further enriched for the cells of interest (e.g., T cells). Here, we present a first‐of‐its‐kind closed system, which effectively removes ~85% of monocytes and ~88% of p...