The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice

• Main Authors: Hanna Langhorst (Author), René Jüttner (Author), Dieter Groneberg (Author), Azadeh Mohtashamdolatshahi (Author), Laura Pelz (Author), Bettina Purfürst (Author), Kai M. Schmidt-Ott (Author), Andreas Friebe (Author), Fritz G. Rathjen (Author)
• Format: Book
• Published: The Company of Biologists, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CAR-like membrane protein (CLMP), an immunoglobulin cell adhesion molecule (IgCAM), has been implicated in congenital short-bowel syndrome in humans, a condition with high mortality for which there is currently no cure. We therefore studied the function of CLMP in a Clmp-deficient mouse model. Altho...