Crushing tablets or sprinkling capsules: Implications for clinical strategy and study performance based on BE studies of rivaroxaban and deferasirox

• Váldodahkkit: Jan Sus (Dahkki), Jan Bosak (Dahkki), Tomas Hauser (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2024-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Administration of oral medicinal products as crushed tablets or open capsules is an important delivery option for patients suffering from dysphagia. To obtain full interchangeability of generics with the original products, demonstration of bioequivalence (BE) between both products administe...