11-Hydroxyeicosatetraenoics induces cellular hypertrophy in an enantioselective manner
BackgroundR/S enantiomers of 11-hydroxyeicosatertraenoic acid (11-HETE) are formed from arachidonic acid by enzymatic and non-enzymatic pathways. 11-HETE is predominately formed by the cytochrome P450 1B1 (CYP1B1). The role of CYP1B1 in the development of cardiovascular diseases is well established....
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Frontiers Media S.A.,
2024-08-01T00:00:00Z.
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