Research Progress on PARP14 as a Drug Target

• Main Authors: Wei Qin (Author), Hong-Jie Wu (Author), Lu-Qi Cao (Author), Hui-Jin Li (Author), Chun-Xia He (Author), Dong Zhao (Author), Lu Xing (Author), Peng-Quan Li (Author), Xi Jin (Author), Hui-Ling Cao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Poly-adenosine diphosphate-ribose polymerase (PARP) implements posttranslational mono- or poly-ADP-ribosylation modification of target proteins. Among the known 18 members in the enormous family of PARP enzymes, several investigations about PARP1, PARP2, and PARP5a/5b have been launched in the past...