The 4th NextGen therapies for SJIA and MAS: part 3 clinical trials in refractory SJIA: historic controls as an alternative to a withdrawal design study

• Váldodahkkit: Fabrizio de Benedetti (Dahkki), Alexei A. Grom (Dahkki), Hermine Brunner (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: BMC, 2024-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract The substantial morbidity and mortality associated with refractory systemic JIA underlies the need for new treatment approaches. However, progress in this area has been limited by the difficulty of enrolling these patients in clinical trials with traditional designs, particularly in patient...