Effects of propofol and its formulation components on macrophages and neutrophils in obese and lean animals

• Main Authors: Luciana Boavista Barros Heil (Author), Fernanda Ferreira Cruz (Author), Mariana Alves Antunes (Author), Cassia Lisboa Braga (Author), Lais Costa Agra (Author), Rebecca Madureira Bose Leão (Author), Soraia Carvalho Abreu (Author), Paolo Pelosi (Author), Pedro Leme Silva (Author), Patricia Rieken Macedo Rocco (Author)
• Format: Book
• Published: Wiley, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We hypothesized whether propofol or active propofol component (2,6‐diisopropylphenol [DIPPH] and lipid excipient [LIP‐EXC]) separately may alter inflammatory mediators expressed by macrophages and neutrophils in lean and obese rats. Male Wistar rats (n = 10) were randomly assigned to receiv...