Beneficial effects of benznidazole in Chagas disease: NIH SaMi-Trop cohort study.

• Main Authors: Clareci Silva Cardoso (Author), Antonio Luiz P Ribeiro (Author), Claudia Di Lorenzo Oliveira (Author), Lea Campos Oliveira (Author), Ariela Mota Ferreira (Author), Ana Luiza Bierrenbach (Author), José Luiz Padilha Silva (Author), Enrico Antonio Colosimo (Author), João Eduardo Ferreira (Author), Tzong-Hae Lee (Author), Michael P Busch (Author), Arthur Lawrence Reingold (Author), Ester Cerdeira Sabino (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The effectiveness of anti-parasite treatment with benznidazole in the chronic Chagas disease (ChD) remains uncertain. We evaluated, using data from the NIH-sponsored SaMi-Trop prospective cohort study, if previous treatment with benznidazole is associated with lower mortality, less advanc...