Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice

• Main Authors: Haichao Zhang (Author), Zheng Ke (Author), Shuangshuang Dong (Author), Yanping Du (Author), Wenjing Tang (Author), Minmin Chen (Author), Weijia Yu (Author), Qun Cheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Elderly male patients are susceptible to develop osteoporosis and sarcopenia, especially those with fragility fractures, hypogonadism, and prostate cancer with androgen deprivation therapy. However, at present, very few treatments are available for men with sarcopenia. Previous preclinical studies i...