Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer

• Main Authors: Mariana Teixeira Rodrigues (Author), Ana Paula Picaro Michelli (Author), Gustavo Felisola Caso (Author), Paloma Ramos de Oliveira (Author), Dorival Mendes Rodrigues-Junior (Author), Mirian Galliote Morale (Author), Joel Machado Júnior (Author), Karina Ramalho Bortoluci (Author), Rodrigo Esaki Tamura (Author), Tamiris Reissa Cipriano da Silva (Author), Cristiano Raminelli (Author), Eric Chau (Author), Biana Godin (Author), Jamile Calil-Silveira (Author), Ileana G. Sanchez Rubio (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anaplastic thyroid cancer (ATC) is an aggressive form of thyroid cancer (TC), accounting for 50% of total TC-related deaths. Although therapeutic approaches against TC have improved in recent years, the survival rate remains low, and severe adverse effects are commonly reported. However, unexplored...