Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor

• Main Authors: Xingkai Liu (Author), Qian Chen (Author), Xuming Ji (Author), Wanchen Yu (Author), Tong Wang (Author), Juanjuan Han (Author), Shumu Li (Author), Jianan Liu (Author), Fangang Zeng (Author), Yao Zhao (Author), Yanyan Zhang (Author), Qun Luo (Author), Shijun Wang (Author), Fuyi Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Descurainia sophia seeds (DS), Astragalus mongholicus (AM), and their formulas are widely used to treat heart failure caused by various cardiac diseases in traditional Chinese medicine practice. However, the molecular mechanism of action of DS and AM has not been completely understood. Herein, we fi...