P53 expression in ischemic rat models after the administration of ketamine and ketamine-xylazine

• Main Authors: Ety Sari Handayani (Author), Zainuri Sabta Nugraha (Author), Kuswati Kuswati (Author), Muhammad Yusuf Hisyam (Author), Untung Widodo (Author), Nurul Hidayah (Author), Sahdella Sahdella (Author), Wimpy Wimpy (Author)
• Format: Book
• Published: Universitas Ahmad Dahlan, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ketamine and ketamine-xylazine are often used as anesthetic drugs in animal models of ischemia. However, their neuroprotective and neurotoxic effects in ischemic animal models that have undergone tBCCAO are still under debate. The protein p53 is a pro-apoptotic factor involved in the cellular mechan...