Dysregulation of Blood-Brain Barrier and Exacerbated Inflammatory Response in Cx47-Deficient Mice after Induction of EAE

Induction of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), in connexin 32 (Cx32) or Cx47 knockout (KO) mice with deficiency in oligodendrocyte gap junctions (GJs) results in a more severe disease course. In particular, Cx47 KO EAE mice experience an ear...

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Main Authors: Filippos Stavropoulos (Author), Elena Georgiou (Author), Irene Sargiannidou (Author), Kleopas A. Kleopa (Author)
Format: Book
Published: MDPI AG, 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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