Dysregulation of Blood-Brain Barrier and Exacerbated Inflammatory Response in Cx47-Deficient Mice after Induction of EAE

• Asıl Yazarlar: Filippos Stavropoulos (Yazar), Elena Georgiou (Yazar), Irene Sargiannidou (Yazar), Kleopas A. Kleopa (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Induction of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), in connexin 32 (Cx32) or Cx47 knockout (KO) mice with deficiency in oligodendrocyte gap junctions (GJs) results in a more severe disease course. In particular, Cx47 KO EAE mice experience an ear...