An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages.

• 主要な著者: Jair L Siqueira-Neto (著者), Seunghyun Moon (著者), Jiyeon Jang (著者), Gyongseon Yang (著者), Changbok Lee (著者), Hong Kee Moon (著者), Eric Chatelain (著者), Auguste Genovesio (著者), Jonathan Cechetto (著者), Lucio H Freitas-Junior (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Leishmaniasis is a tropical disease threatening 350 million people from endemic regions. The available drugs for treatment are inadequate, with limitations such as serious side effects, parasite resistance or high cost. Driven by this need for new drugs, we developed a high-content, high-throughput...