Rutin Protects Fibroblasts from UVA Radiation through Stimulation of Nrf2 Pathway

• Main Authors: Elisabetta Tabolacci (Author), Giuseppe Tringali (Author), Veronica Nobile (Author), Sara Duca (Author), Michela Pizzoferrato (Author), Patrizia Bottoni (Author), Maria Elisabetta Clementi (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study explores the photoprotective effects of rutin, a bioflavonoid found in some vegetables and fruits, against UVA-induced damage in human skin fibroblasts. Our results show that rutin increases cell viability and reduces the high levels of ROS generated by photo-oxidative stress (1 and 2 h o...