Influence of Surface-Modification via PEGylation or Chitosanization of Lipidic Nanocarriers on In Vivo Pharmacokinetic/Pharmacodynamic Profiles of Apixaban

• Main Authors: Mohamed F. Zaky (Author), Taha M. Hammady (Author), Shadeed Gad (Author), Abdullah Alattar (Author), Reem Alshaman (Author), Ann Hegazy (Author), Sawsan A. Zaitone (Author), Mamdouh Mostafa Ghorab (Author), Mohamed A. Megahed (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanostructured lipid carriers (NLCs) have been proven to significantly improve the bioavailability and efficacy of many drugs; however, they still have many limitations. These limitations could hinder their potential for enhancing the bioavailability of poorly water-soluble drugs and, therefore, req...