Real-World Efficacy and Safety of Oral Tofacitinib in Patients with Refractory Moderate to Severe Atopic Dermatitis: A Multicenter Retrospective Study

• Những tác giả chính: Sandipan Dhar (Tác giả), Abhishek De (Tác giả), Aarti Sarda (Tác giả), Kiran Godse (Tác giả), Koushik Lahiri (Tác giả)
• Định dạng: Sách
• Được phát hành: Wolters Kluwer Medknow Publications, 2024-08-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background: Atopic dermatitis (AD) has a complex etiology that includes Th2 polarization, which is accompanied by the cytokines IL4, IL-5, IL-13, and IL-31, as well as Th17 and Th22, and in chronic lesions, Th1 cells. Tofacitinib inhibits Th1-, Th2-, and Th17-associated cytokines by selectively bloc...