Emerging Albumin-Binding Anticancer Drugs for Tumor-Targeted Drug Delivery: Current Understandings and Clinical Translation

• Autori principali: Hanhee Cho (Autore), Seong Ik Jeon (Autore), Cheol-Hee Ahn (Autore), Man Kyu Shim (Autore), Kwangmeyung Kim (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Albumin has shown remarkable promise as a natural drug carrier by improving pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The exogenous or endogenous albumin enhances the circulatory half-lives of anticancer drugs and passively target the tumors by the enhanced perme...