GABAergic signaling as therapeutic target for Autism Spectrum Disorders
GABA, the main inhibitory neurotransmitter in the adult brain, early in postnatal life exerts a depolarizing and excitatory action. This depends on accumulation of chloride inside the cell via the cation-chloride importer NKCC1, being the expression of the chloride exporter KCC2 very low at birth. T...
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Format: | Book |
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Frontiers Media S.A.,
2014-07-01T00:00:00Z.
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A1234.567 |
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