The Neuroprotective Effect of Amitriptyline on Radiation-Induced Impairment of Hippocampal Neurogenesis

• Main Authors: Yu Rong Guo (Author), Zi Wei Liu (Author), Shuang Peng (Author), Meng Yun Duan (Author), Jing Wei Feng (Author), Wei Feng Wang (Author), Yan Hua Xu (Author), Xi Tang (Author), Xiang Zhi Zhang (Author), Bo Xu Ren (Author), Feng Ru Tang (Author)
• Format: Book
• Published: SAGE Publishing, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The radioprotective effect of amitriptyline, an inhibitor of acid sphingomyelinase (ASMase), on radiation-induced impairment of hippocampal neurogenesis, loss of interneuron, and animal weight changes was investigated in BALB/c mice by immunostaining of biomarkers for cell division (Ki67), immature...