Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics

• Main Authors: Chiara Giannasi (Author), Laura Mangiavini (Author), Stefania Niada (Author), Andrea Colombo (Author), Elena Della Morte (Author), Valeria Vismara (Author), Andrea Ambrosanio (Author), Paolo Savadori (Author), Sara Casati (Author), Giuseppe M. Peretti (Author), Anna Teresa Brini (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a highly prevalent joint disease still lacking effective treatments. Its multifactorial etiology hampers the development of relevant preclinical models to evaluate innovative therapeutic solutions. In the last decade, the potential of Mesenchymal Stem Cell (MSC) secretome, or...