The M-Channel Blocker Linopirdine Is an Agonist of the Capsaicin Receptor TRPV1

Abstract.: Linopirdine is a well known blocker of voltage-gated potassium channels from the Kv7 (or KCNQ) family that generate the so called M current in mammalian neurons. Kv7 subunits are also expressed in pain-sensing neurons in dorsal root ganglia, in which they modulate neuronal excitability. I...

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Main Authors: Cristian Neacsu (Author), Alexandru Babes (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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