A Theranostic Nanocomplex Combining with Magnetic Hyperthermia for Enhanced Accumulation and Efficacy of pH-Triggering Polymeric Cisplatin(IV) Prodrugs

• Autori principali: Yang Qu (Autore), Zhiqi Wang (Autore), Miao Sun (Autore), Tian Zhao (Autore), Xuanlei Zhu (Autore), Xiaoli Deng (Autore), Man Zhang (Autore), Ying Xu (Autore), Hongfei Liu (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Although polymeric platinum(IV) (Pt(IV)) prodrugs can reduce the side effects of cisplatin, the efficacy of the prodrug is still limited by its non-targeted distribution, poor penetration in deep tumor tissue, and low cytotoxicity in tumor cells. To improve the clinical potential of polymeric prodru...