Optimization of Lipid Nanoparticles by Response Surface Methodology to Improve the Ocular Delivery of Diosmin: Characterization and In-Vitro Anti-Inflammatory Assessment

• Main Authors: Elide Zingale (Author), Salvatore Rizzo (Author), Angela Bonaccorso (Author), Valeria Consoli (Author), Luca Vanella (Author), Teresa Musumeci (Author), Angelo Spadaro (Author), Rosario Pignatello (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diosmin is a flavonoid with a great variety of biological activities including antioxidant and anti-inflammatory ones. Its cytoprotective effect in retinal pigment epithelium cells under high glucose conditions makes it a potential support in the treatment of diabetic retinopathy. Despite its benefi...