rBMSC/Cav-1F92A Mediates Oxidative Stress in PAH Rat by Regulating SelW/14-3-3η and CA1/Kininogen Signal Transduction

• Hoofdauteurs: Wan-cheng Yu (Auteur), Hai-ying Chen (Auteur), Hong-li Yang (Auteur), Peng Xia (Auteur), Cheng-wei Zou (Auteur), Tong-wen Sun (Auteur), Le-xin Wang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2019-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background/Objectives. Carbonic anhydrase 1 (CA1)/kininogen and selenoprotein W (SelW)/14-3-3η signal transduction orchestrate oxidative stress, which can also be regulated by nitric oxide (NO). The mutated caveolin-1 (Cav-1F92A) gene may enhance NO production. This study explored the effect of Cav-...