A Novel Network Science and Similarity-Searching-Based Approach for Discovering Potential Tumor-Homing Peptides from Antimicrobials

• Main Authors: Maylin Romero (Author), Yovani Marrero-Ponce (Author), Hortensia Rodríguez (Author), Guillermin Agüero-Chapin (Author), Agostinho Antunes (Author), Longendri Aguilera-Mendoza (Author), Felix Martinez-Rios (Author)
• 格式: 图书
• 出版: MDPI AG, 2022-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Peptide-based drugs are promising anticancer candidates due to their biocompatibility and low toxicity. In particular, tumor-homing peptides (THPs) have the ability to bind specifically to cancer cell receptors and tumor vasculature. Despite their potential to develop antitumor drugs, there are few...