Risk-Adapted Treatment Strategies with Pre-Irradiation Chemotherapy in Pediatric Medulloblastoma: Outcomes from the Polish Pediatric Neuro-Oncology Group

• Main Authors: Marta Perek-Polnik (Author), Anne Cochrane (Author), Jinli Wang (Author), Marzanna Chojnacka (Author), Monika Drogosiewicz (Author), Iwona Filipek (Author), Ewa Swieszkowska (Author), Magdalena Tarasinska (Author), Wiesława Grajkowska (Author), Joanna Trubicka (Author), Paweł Kowalczyk (Author), Bożenna Dembowska-Bagińskai (Author), Mohamed S. Abdelbaki (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Craniospinal irradiation (CSI) has been a major component of the standard of care treatment backbone for childhood medulloblastoma. However, chemotherapy regimens have varied based on protocol, patient age, and molecular subtyping. In one of the largest studies to date, we analyzed treatment outcome...