Transcriptomic signature of Leishmania infected mice macrophages: a metabolic point of view.

• Main Authors: Imen Rabhi (Author), Sameh Rabhi (Author), Rym Ben-Othman (Author), Axel Rasche (Author), Adriani Daskalaki (Author), Bernadette Trentin (Author), David Piquemal (Author), Béatrice Regnault (Author), Albert Descoteaux (Author), Lamia Guizani-Tabbane (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We analyzed the transcriptional signatures of mouse bone marrow-derived macrophages at different times after infection with promastigotes of the protozoan parasite Leishmania major. Ingenuity Pathway Analysis revealed that the macrophage metabolic pathways including carbohydrate and lipid metabolism...