Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes-A More Selective Anticancer Treatment?

Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes-A More Selective Anticancer Treatment?

Based on their drug delivery properties and activity against tumors, we combined PAMAM dendrimers with various platinum(IV) complexes in order to provide an improved approach of anticancer treatment. Platinum(IV) complexes were linked to terminal NH<sub>2</sub> moieties of PAMAM dendrime...

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Main Authors: Yvonne Lerchbammer-Kreith (Author), Michaela Hejl (Author), Petra Vician (Author), Michael A. Jakupec (Author), Walter Berger (Author), Mathea S. Galanski (Author), Bernhard K. Keppler (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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