Low Concentration of Rapamycin Inhibits Hemangioma Endothelial Cell Proliferation, Migration, and Vascular Tumor Formation in Mice

• Main Authors: Ningning Zheng, PhD (Author), Xudong Ding, MD (Author), Rabita Jahan (Author)
• Formato: Livro
• Publicado em: Elsevier, 2014-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Vascular endothelial cell excessive proliferation is the main biological behavior of hemangioma. Rapamycin regulates the growth of endothelial cells by inhibiting mammalian target of rapamycin (mTOR). Thus hemangioma accompanied by excessive mTOR activation should be sensitive to rapamyc...