Paeonol enhances macrophage phagocytic function by modulating lipid metabolism through the P53-TREM2 axis

• Main Authors: Jifei Miao (Author), Xiaoming Liu (Author), Yuanpin Liao (Author), Yiwen Li (Author), Yingyan Kuang (Author), Juanxia Zheng (Author), Zigang Li (Author), Jiao Lan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The emerging concept of immunometabolism highlights the interplay between lipid metabolism and phagocytosis in macrophages. Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) has been identified as an essential modulator of both lipid metabolism and phagocytic function in macroph...