Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis
SUMMARY Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have de...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2013-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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