Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptors

Molecular docking studies of N-substituted 4-methoxy-6-oxo-1-aryl-pyridazine-3-carboxamide derivatives as potential modulators of glutamate receptors

Introduction: The virtual target-oriented screening is a necessary stage of modern drug-design. In the present study, the affinity of pyridazine derivatives for the most promising antiparkinsonian biotargets - I-III groups of metabotropic and ionotropic NMDA-glutamate receptors - was evaluated. Mate...

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Main Authors: Hanna I. Severina (Author), Victoriya A. Georgiyants (Author), Sergiy M. Kovalenko (Author), Natalia V. Avdeeva (Author), Artem I. Yarcev (Author), Svetlana N. Prohoda (Author)
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Published: Belgorod National Research University, 2020-03-01T00:00:00Z.
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