rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan.

• Main Authors: Elfadil Abass (Author), Nadine Bollig (Author), Katharina Reinhard (Author), Bärbel Camara (Author), Durria Mansour (Author), Alexander Visekruna (Author), Michael Lohoff (Author), Ulrich Steinhoff (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: For effective control of visceral leishmaniasis (VL) in East Africa, new rapid diagnostic tests are required to replace current tests with low sensitivity. The aim of this study is to improve diagnosis of VL in East Africa by testing a new antigen from an autochthonous L. donovani strain...