NLRP3 inflammasome and its inhibitors: a review

• Main Authors: Bo-Zong eShao (Author), Zhe-qi eXu (Author), Bin-Ze eHan (Author), Ding-Feng eSu (Author), Chong eLiu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammasomes are newly recognized, vital players in innate immunity. The best characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as pyrin domain-co...