NLRP3 inflammasome and its inhibitors: a review

• Autori principali: Bo-Zong eShao (Autore), Zhe-qi eXu (Autore), Bin-Ze eHan (Autore), Ding-Feng eSu (Autore), Chong eLiu (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Inflammasomes are newly recognized, vital players in innate immunity. The best characterized is the NLRP3 inflammasome, so-called because the NLRP3 protein in the complex belongs to the family of nucleotide-binding and oligomerization domain-like receptors (NLRs) and is also known as pyrin domain-co...