MicroRNA-20b Promotes Cardiac Hypertrophy by the Inhibition of Mitofusin 2-Mediated Inter-organelle Ca2+ Cross-Talk

• Hauptverfasser: Yue Qiu (VerfasserIn), Rongchao Cheng (VerfasserIn), Chaoqi Liang (VerfasserIn), Yuan Yao (VerfasserIn), Wenhao Zhang (VerfasserIn), Jie Zhang (VerfasserIn), Mingyu Zhang (VerfasserIn), Baiyan Li (VerfasserIn), Chaoqian Xu (VerfasserIn), Rong Zhang (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2020-03-01T00:00:00Z.
• Schlagworte: article
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MicroRNA (miRNA) and mitofusin-2 (Mfn2) are important in the development of cardiac hypertrophy, but the target relationship and mechanism associated with Ca2+ handling between SR and mitochondria under hypertrophic condition is not established. Mfn2 expression, Mfn2-mediated interorganelle Ca2+ cro...