MicroRNA-20b Promotes Cardiac Hypertrophy by the Inhibition of Mitofusin 2-Mediated Inter-organelle Ca2+ Cross-Talk

• المؤلفون الرئيسيون: Yue Qiu (مؤلف), Rongchao Cheng (مؤلف), Chaoqi Liang (مؤلف), Yuan Yao (مؤلف), Wenhao Zhang (مؤلف), Jie Zhang (مؤلف), Mingyu Zhang (مؤلف), Baiyan Li (مؤلف), Chaoqian Xu (مؤلف), Rong Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2020-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

MicroRNA (miRNA) and mitofusin-2 (Mfn2) are important in the development of cardiac hypertrophy, but the target relationship and mechanism associated with Ca2+ handling between SR and mitochondria under hypertrophic condition is not established. Mfn2 expression, Mfn2-mediated interorganelle Ca2+ cro...