A stepwise strategy integrating metabolomics and pseudotargeted spectrum-effect relationship to elucidate the potential hepatotoxic components in Polygonum multiflorum

• Main Authors: Yunfei Song (Author), Jianbo Yang (Author), Xiaowen Hu (Author), Huiyu Gao (Author), Pengfei Wang (Author), Xueting Wang (Author), Yue Liu (Author), Xianlong Cheng (Author), Feng Wei (Author), Shuangcheng Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polygonummultiflorum (PM) Thunb., a typical Chinese herbal medicine with different therapeutic effect in raw and processed forms, has been used worldwide for thousands of years. However, hepatotoxicity caused by PM has raised considerable concern in recent decades. The exploration of toxic component...