Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis

• Main Authors: Sze Wan Hung (Author), Massimiliano Gaetani (Author), Yiran Li (Author), Zhouyurong Tan (Author), Xu Zheng (Author), Ruizhe Zhang (Author), Yang Ding (Author), Gene Chi Wai Man (Author), Tao Zhang (Author), Yi Song (Author), Yao Wang (Author), Jacqueline Pui Wah Chung (Author), Tak Hang Chan (Author), Roman A. Zubarev (Author), Chi Chiu Wang (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endometriosis is a common chronic gynecological disease with endometrial cell implantation outside the uterus. Angiogenesis is a major pathophysiology in endometriosis. Our previous studies have demonstrated that the prodrug of epigallocatechin gallate (ProEGCG) exhibits superior anti-endometriotic...